Table 3. Associations of self-reported race/ethnicity with self-reported BCRL status.
| n | # Eventsa | Unadjusted model | Base Modelb | Further adjusted for age BC Dx, baseline BMI, baseline PA, comorbidity, HTN | |
|---|---|---|---|---|---|
| HR (95 % CI) | HR (95 % CI) | HR (95 % CI) | |||
| Race/ethnicity from self-report | |||||
| White | 1969 | 133 | Ref | Ref | Ref |
| African American | 210 | 27 | 2.04 (1.35, 3.08) | 1.60 (1.04, 2.47) | 1.47 (0.94, 2.30) |
| Hispanic | 351 | 33 | 1.47 (1.00, 2.15) | 1.28 (0.86, 1.90) | 1.18 (0.78, 1.77) |
| Asian | 353 | 30 | 1.31 (0.88, 1.95) | 1.18 (0.78, 1.79) | 1.24 (0.81, 1.92) |
| Other | 70 | 7 | 1.57 (0.73, 3.36) | 1.20 (0.55, 2.59) | 1.21 (0.56, 2.61) |
| Genetic ancestryc | |||||
| European ancestry | – | – | Ref | Ref | |
| African ancestry | – | – | 2.50 (1.43, 4.36) | 1.93 (1.08, 3.43) | 1.73 (0.96, 3.14) |
| Native American ancestry | – | – | 2.70 (0.79, 9.23) | 1.91 (0.52, 7.07) | 1.33 (0.32, 5.51) |
| Asian ancestry | – | – | 1.23 (0.73, 2.05) | 1.14 (0.66, 1.94) | 1.21 (0.69, 2.11) |
Follow-up starting at 6 months postbreast cancer diagnosis until BCRL self-report or date of last patient contact (12- or 48-month follow-up), whichever occurred first
Cox proportional hazards models, adjusted for education, household income, employment, AJCC stage, breast and lymph node surgery, number of lymph nodes examined, chemotherapy, radiation therapy
The estimated percentages of African, Asian and Native American ancestry for each patient were entered in the models as continuous, each with a range of 0–1 and European ancestry set as the default reference. Thus, the HRs with each of the three ancestries should be interpreted as the hazards of a “genetically pure” individual of the respective ancestry relative to a genetically pure individual of European ancestry