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. Author manuscript; available in PMC: 2017 Oct 30.
Published in final edited form as: Gene. 2016 Aug 6;592(1):209–214. doi: 10.1016/j.gene.2016.08.005

Fig. 1.

Fig. 1

Analysis of the canine cbr1 promoter. (A) Schematic representation of canine cbr1 promoter constructs showing seven potential binding sites for Sp1. Canonical Sp1 binding sites (GGGCGG) are represented with white boxes. Non-canonical Sp1 binding sites (GCCACGCC) are represented by grey boxes. DNA sequence comparison (Beagle vs Boxer GenBank reference sequence) corresponding to variant D(B) Luciferase activities of the canine cbr1 constructs −750/−21 and −230/−21 in MDCK cells. Normalized luciferase activities were expressed relative to the values from −230/−21cbr1 construct that was assigned an arbitrary value of 100. Data represent the mean ± standard deviation of three independent experiments.