Table 7. Performance of single variable post-transplant (7a upper table) and pre-transplant (7b, lower table) models based on IR of CD154+TcM in training and validation sets.

Cohort	AUC	Cut value	Sensitivity	95% CI	Specificity	95% CI	PPV	95% CI	NPV	95% CI
Training set(n=98)	0.878	0.0420 (1.10 on raw IR scale)	92% (22/24)	72%, 99%	84% (62/74)	73%, 91%	65% (22/34)	46%, 80%	97% (62/64)	88%, 99%
Validation set(n=64)	0.791	0.042 (1.10 on raw IR scale)	84% (16/19)	60%, 96%	80% (36/45)	65%, 90%	64% (16/25)	43%, 81%	92% (36/39)	78%, 98%
Cohort	AUC	Cut value	Sensitivity	95% CI	Specificity	95% CI	PPV	95% CI	NPV	95% CI
Training set(n=49)	0.82	0.088 (1.23 on raw IR scale)	80% (20/25)	59%, 92%	71% (17/24)	49%, 87%	74% (20/27)	53%, 88%	77% (17/22)	54%, 91%
Validation set (n=33)	0.842	0.088 (1.23 on raw IR scale)	57% (8/14)	30%, 81%	89% (17/19)	65%, 98%	80% (8/10)	44%, 96%	74% (17/23)	51%, 89%