Table 3.
Intraoperative Secondary Insult data for Orthopedic Surgery in Patients with moderate-severe Traumatic Brain Injury (n=78). Data are presented as number (%) or median (range).
| Overall N=78 |
Orthopedic Surgery within 2 days of TBI (n=41) |
Orthopedic Surgery 3–14 days after TBI (n=37) |
P (95% CI) |
|
|---|---|---|---|---|
| Systemic Hypotension (SBP <90 mmHg) | 47 (60%) | 25(61%) | 22 (59%) | 0.89 (0.38, 2.33) |
| Lowest SBP (mmHg) | 50 (0–88) | 87 (65–88) | 78 (0–88) | 0.66 (−6.77, 7.13) |
| Intracranial Hypertension (ICP >20mmHg) | 10/20 (50%) | 5/8 (62%) | 5/12 (42%) | 0.60 (0.24, 3.35) |
| Highest ICP (mmHg) | 19 (10–44) | 21 (14–44) | 19 (10–38) | 0.65 (−6.37, 10.62) |
| Cerebral Hypotension (CPP <50 mmHg) | 9/20 (45%) | 4/8 (50%) | 5/12 (42%) | 0.55 (0.17, 2.80) |
| Lowest CPP (mmHg) | 56 (29–101) | 51 (29–83) | 58 (40–101) | 0.65 (−22.79, 12.62) |
| Hypercarbia (ETCO2> 40 mmHg) | 25 (32%) | 13 (32%) | 12 (32%) | 0.98 (0.50, 2.95) |
| Highest ETCO2 (mmHg) | 51 (30–68) | 42 (30–68) | 42 (30–60) | 0.50 (−4.38, 4.45) |
| Hypocarbia (ETCO2< 30 (mmHg) | 33 (29%) | 11 (27%) | 12 (32%) | 0.23 (0.50, 3.47) |
| Lowest ETCO2 (mmHg) | 31 (20–51) | 31 (20–41) | 31 (23–51) | 0.72 (−3.54, 0.87) |
| Hyperthermia (core temperature >38°C) | 9 (12%) | 3 (7.5%) | 6 (16%) | 0.02 (0.09, 1.17) |
| Highest temperature (°C) | 37.3 (35.6–39.1) | 37.3 (36.5–38.3) | 37.4 (35.6–39.1) | 0.09 (−0.64, 0.11) |
| Hyperglycemia (Blood glucose >200 mg/dL) | 2/30 (6.7%) | 1/13(7.7%) | 1/17(5.9%) | 0.47 (0.05, 14.92) |
| Highest blood glucose (mg/dL) | 129 (83–293) | 148 (87–293) | 122 (83–240) | 0.14 (−23.00, 46.56) |
SBP= Systolic Blood Pressure. ICP= Intracranial Pressure. CPP=Cerebral Perfusion Pressure. ETCO2= End tidal CO2