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. Author manuscript; available in PMC: 2017 Mar 15.
Published in final edited form as: Int J Radiat Oncol Biol Phys. 2015 Dec 15;94(4):800–807. doi: 10.1016/j.ijrobp.2015.11.046

Table 3.

Incidence rate ratio (RR) of thyroid cancer by level of exposure to alkylating agents (alkylating agent score) and dose of radiation to the thyroid gland. Modified after Veiga et al. (15)

Radiation Dose (Gy)

Exposure to
Alkylating
Agents (Score)
≤20

0
RRa
0–5
RRb
0–20
RRb
>20
RRb
Not exposed (0) 1.0c 1.0c 1.0c 1.0c
Low/medium(1–2) 1.8 2.5 2.3 1.0
Highly exposed (3) 9.4 5.5 2.8 1.0
P (trend) 0.08 0.02 0.009 0.99
a

Adjusted for sex, natural log of attained age, type of first cancer (HL, leukemia, others)

b

Adjusted for sex, natural log of attained age, type of first cancer and radiation dose on continuous scale

c

Reference category