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. 2016 Aug 25;99(3):580–594. doi: 10.1016/j.ajhg.2016.07.002

Figure 3.

Figure 3

Estimated Changes in Effective Population Size over Time

The estimation was based on PSMC analysis of single genomes from three modern human groups with deeply sequenced genomes in this study (33 TBN, 5 SHP, and 39 HAN). To overcome uncertain date estimates due to a lack of confidence in the true value of the mutation rate, we scaled time in units of 2 μT (where μ is the mutation rate and T is time in generations). We also provide an absolute estimation of time (top) under the assumption of a fast mutation rate of 1.0 × 10−9 or a slow mutation rate of 0.5 × 10−9 per site per year.