Figure 2.

Clinical Features of the Analyzed Subjects

(A) Individual KN10. Fundus pictures (at age 53 years) reveal macular coalescent hypochromatic lesions in the right eye and minor macular changes in the left eye. Pure tone audiograms at age 57 years (black lines) and 59 years (red lines) show mild hearing impairment at higher frequencies compared to the normal range for gender and age, indicated by the shaded area.⁸

(B) Individual 2702r34. Fundus examination at age 65 years highlights attenuated vessels and degenerative changes in the posterior pole. Audiograms at age 66 years (black lines) and 77 years (red lines) show clear hearing loss at most frequencies. Abbreviations are as follows: OD, right eye; OS, left eye; RE, right ear; and LE, left ear.