Table 3. Agreement between MDRD Study equation and other equations.
| GFR category | MDRD Study | Categorical agreement | Diagnostic agreement at specific eGFR cutoffs | |||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| G1 | G2 | G3a | G3b | G4 | G5 | Total | % | Weighted kappa (95% CI) | Kappa at 60 mL/min/1.73 m2 (95% CI) | Kappa at 45 mL/min/1.73 m2 (95% CI) | ||
| CKD-EPICr | G1 | 119 | 297 | 0 | 0 | 0 | 0 | 416 | 76.0 | 0.521 (0.474–0.568) |
0.729 (0.662–0.796) |
0.961 (0.907–1.000) |
| G2 | 0 | 927 | 56 | 0 | 0 | 0 | 983 | |||||
| G3a | 0 | 0 | 56 | 02 | 0 | 0 | 58 | |||||
| G3b | 0 | 0 | 0 | 18 | 0 | 0 | 18 | |||||
| G4 | 0 | 0 | 0 | 0 | 6 | 0 | 6 | |||||
| G5 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | |||||
| CKD-EPICysC | G1 | 113 | 1,047 | 43 | 7 | 2 | 0 | 1,212 | 20.3 | 0.067 (0.047–0.087) |
0.259 (0.173–0.346) |
0.415 (0.217–0.613) |
| G2 | 4 | 169 | 54 | 4 | 4 | 0 | 235 | |||||
| G3a | 2 | 7 | 13 | 2 | 0 | 0 | 24 | |||||
| G3b | 0 | 1 | 2 | 6 | 0 | 1 | 10 | |||||
| G4 | 0 | 0 | 0 | 1 | 0 | 0 | 1 | |||||
| G5 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | |||||
| CKD-EPICr-CysC | G1 | 113 | 865 | 4 | 0 | 0 | 0 | 982 | 33.3 | 0.139 (0.111–0.167) |
0.402 (0.313–0.492) |
0.595 (0.415–0.776) |
| G2 | 6 | 358 | 92 | 5 | 0 | 0 | 461 | |||||
| G3a | 0 | 1 | 15 | 7 | 3 | 0 | 26 | |||||
| G3b | 0 | 0 | 1 | 7 | 3 | 0 | 11 | |||||
| G4 | 0 | 0 | 0 | 1 | 0 | 1 | 2 | |||||
| G5 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | |||||
| LMrevised | G1 | 103 | 6 | 0 | 0 | 0 | 0 | 109 | 93.8 | 0.823 (0.788–0.859) |
0.737 (0.674–0.799) |
0.962 (0.910–1.000) |
| G2 | 16 | 1,197 | 41 | 0 | 0 | 0 | 1,254 | |||||
| G3a | 0 | 21 | 70 | 1 | 0 | 0 | 92 | |||||
| G3b | 0 | 0 | 1 | 13 | 0 | 0 | 14 | |||||
| G4 | 0 | 0 | 0 | 6 | 6 | 0 | 12 | |||||
| G5 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | |||||
| Total | 119 | 1,224 | 112 | 20 | 6 | 1 | 1,482 | |||||
Abbreviations: CI, confidence interval; See Table 1.