Table 3. Clinical characteristics of patients with KPC-2-producing K. pneumoniae and OXA-232-producing K. pneumoniae isolates.
| Characteristic | N (%) of patients | P values | ||
|---|---|---|---|---|
| Total (n = 69) | KPC-2 (n = 24) | OXA-232 (n = 45) | ||
| Age (mean ± SD) | 64.6 ± 11.8 | 66.9 ± 8.6 | 63.4 ± 13.1 | 0.189 |
| Male gender | 53 (76.8) | 19 (79.2) | 34 (75.6) | 0.969 |
| Specimen | 0.059 | |||
| Respiratory | 31 (44.9) | 6 (25.0) | 25 (55.6) | |
| Urine | 17 (24.6) | 8 (33.4) | 9 (20.0) | |
| Wound or pus | 9 (13.1) | 6 (25.0) | 3 (6.7) | |
| Blood | 5 (7.3) | 2 (8.3) | 3 (6.7) | |
| Others | 7 (10.1) | 2* (8.3) | 5† (11.0) | |
| ICU hospitalization | 34 (49.3) | 11 (45.8) | 23 (51.1) | 0.869 |
| Hospitalization days [median (range)] | ||||
| Before CPE isolation | 17 (1–187) | 40 (2–142) | 16 (1–187) | 0.006 |
| After CPE isolation | 21 (1–132) | 30 (3–124) | 12 (1–132) | 0.142 |
| Died during hospitalization | 19 (27.5) | 5 (20.8) | 14 (31.1) | 0.486 |
*These two isolates were recovered from bile juice; †These five isolates were recovered from catheter tips (n=3), ascites (n=1), and bile juice (n=1).
Abbreviations: KPC, Klebsiella pneumoniae carbapenemase; OXA, oxacillinase; ICU, intensive care unit; CPE, carbapenemase-producing Enterobacteriaceae.