Table 3. Univariate and multivariate analysis of the association between chromosomes with structural abnormalities and known multiple myeloma (MM) prognostic factors.

Prognostic factors and chromosomes	Univariate analysis			Multivariate analysis
	Odds ratio	95% CI	P value	Odds ratio	95% CI	P value
IgG > 7 g/dL or IgA > 5 g/dL
Chromosome 1q	2.284	1.174–4.443	0.015	2.017	1.014–4.013	0.046
Chromosome 3	3.075	1.031–9.171	0.044	2.286	0.737–7.089	0.152
Lambda type
Chromosome 3	2.621	1.035–6.633	0.042	2.132	0.816–5.571	0.122
Chromosome 6	2.634	1.149–6.038	0.022	2.26	0.961–5.311	0.062
Calcium > 12 mg/dL
Chromosome 1p	3.584	1.176–10.921	0.025	2.019	0.536–7.601	0.299
Chromosome 4	16.364	5.041-53.118	< 0.001	7.656	1.831–32.011	0.005
Chromosome 5	9.091	2.524–32.749	0.001	3.248	0.588–17.924	0.177
Chromosome 11	5.765	1.680–19.775	0.005	1.103	0.215–5.662	0.906
Chromosome 12	4.379	1.304–14.711	0.017	2.047	0.447–9.377	0.356
Chromosome 13	3.991	1.038–15.353	0.044	1.644	0.295–9.174	0.571
Chromosome 14	6.864	2.304–20.448	0.001	1.896	0.428–8.412	0.400
Creatinine > 2 mg/dL
Chromosome 13	4.238	1.670–10.758	0.002	3.095	1.133–8.452	0.028
Chromosome 14	2.865	1.290–6.362	0.010	1.815	0.734–4.490	0.197
Chromosome 15	2.894	1.088–7.701	0.033	1.971	0.677–5.742	0.214
β2-microglobulin > 5.5 mg/L
Chromosome 1p	2.641	1.374–5.078	0.004	1.876	0.917–3.838	0.085
Chromosome 1q	2.011	1.173–3.448	0.011	1.079	0.548–2.124	0.827
Chromosome 5	2.995	1.055–8.503	0.039	1.472	0.462–4.690	0.513
Chromosome 9	2.686	1.050–6.873	0.039	1.57	0.560–4.404	0.371
Chromosome 15	4.110	1.495–11.299	0.006	2.216	0.738–6.653	0.156
Chromosome 19	2.953	1.346–6.475	0.007	2.022	0.805–5.081	0.134

Abbreviation: CI, confidence interval.