Fig. 5.

Consistency measures for the established predictive models usign 8-fold cross-validation. Each figure compares the predicted model for all N = 53 patients to a model using the same predictor variables but calculated on 7 out of 8 folds only, each time leaving the remaining fold as unknown test set. This procedure is repeated 8 times on the 8 non overlapping folds, so that every patient was once a test case. All models (A.–E.) show a remarkably high coincidence with the predicting model for every of the 53 patients (R² between 0.89 and 0.98). 2y-ARR: two-years annual relapse rate; EDSS: Expanded Disability Status Scale; CES-D: Center for Epidemiologic Studies Depression Scale; FSMC-cog: cognitive subscore of the Fatigue Scale for Motor and Cognitive Functions.