Table 1.

Similarity search results of orthosteric antagonists.

Tanimoto coefficienta	Numberb	Percentc
0 < T ≤ 0.5	0	0%
0.5 < T ≤ 0.6	2	3.45%
0.6 < T ≤ 0.7	1	1.72%
0.7 < T ≤ 0.8	28	48.28%
0.8 < T ≤ 0.9	12	20.69%
0.9 < T ≤ 1.0	15	25.86%
Total	58	100.00%

^aTanimoto coefficient is the index of similarity.

^bNumber is the number of compounds within in the corresponding threshold value of Tanimoto coefficient.

^cPercent is percentage of the number of compounds.