Table 4.

The validation results of selected six GALAHAD models.

Model	N_Hits	Specificity	Energy	Pareto	Haa	Htb	HRA c	IEI d	CAI e
O-01	6	2.30	12.39	0	48	56	100.00%	3.429	3.429
O-12	7	2.37	41.35	0	48	164	100.00%	1.171	1.171
O-20	6	2.18	0.12	0	48	64	100.00%	3.000	3.000
O-14	6	2.50	−0.05	0	48	91	100.00%	2.110	2.110

^aHa is the number of active compounds screened by a pharmacophore model.

^bHt is the total number of compounds screened by a pharmacophore model.

^c HRA represents the ability to identify active compounds from the test set.

^d IEI represents the ability to identify active compounds from nonactive compounds.

^e CAI is the comprehensive appraisal index.