Table 9.
Summary of organ weights.
Group (mg/kg bw/d) | Organ weight (g) | |||||||||||
---|---|---|---|---|---|---|---|---|---|---|---|---|
Body weight | Brain | Liver | Kidneys | Heart | Thymus | Spleen | Testes or uterus | Epididymides or ovaries | Adrenals | Thyroids | ||
Males | ||||||||||||
Control (n = 10) | Mean | 422.0 | 2.16 | 10.00 | 2.28 | 1.14 | 0.44 | 0.71 | 3.49 | 1.62 | 0.077 | 0.028 |
SD | 17.52 | 0.16 | 0.96 | 0.20 | 0.09 | 0.12 | 0.10 | 0.34 | 0.09 | 0.01 | 0.01 | |
180 (n = 10) | Mean | 421.8 | 2.19 | 10.77 | 2.38 | 1.14 | 0.40 | 0.77 | 3.51 | 1.65 | 0.074 | 0.023 |
SD | 25.26 | 0.12 | 0.99 | 0.26 | 0.19 | 0.08 | 0.08 | 0.34 | 0.20 | 0.02 | 0.01 | |
±% | 0.0 | 1 | 8 | 5 | 0 | −8 | 9 | 1 | 2 | −4 | −19 | |
SS | ∗ | |||||||||||
300 (n = 10) | Mean | 393.1 | 2.11 | 9.83 | 2.33 | 1.20 | 0.32 | 0.80 | 2.70 | 1.36 | 0.085 | 0.021 |
SD | 28.39 | 0.10 | 0.77 | 0.26 | 0.14 | 0.06 | 0.11 | 0.74 | 0.15 | 0.01 | 0.01 | |
±% | −7 | −2 | −2 | 3 | 5 | −26 | 13 | −23 | −16 | 10 | −26 | |
SS | ∗ | ∗∗ | ∗∗ | ∗∗ | ∗∗ | |||||||
375 (n = 9) | Mean | 377.0 | 2.06 | 9.51 | 2.22 | 1.24 | 0.30 | 0.71 | 1.42 | 1.14 | 0.093 | 0.023 |
SD | 26.43 | 0.14 | 0.99 | 0.25 | 0.22 | 0.05 | 0.10 | 0.68 | 0.12 | 0.01 | 0.00 | |
±% | −11 | −4 | −5 | −3 | 9 | −31 | 1 | −59 | −30 | 20 | −16 | |
SS | ∗∗ | ∗∗ | ∗∗ | ∗∗ | ∗ | |||||||
| ||||||||||||
Females | ||||||||||||
Control (n = 10) | Mean | 241.9 | 1.94 | 6.63 | 1.61 | 0.83 | 0.41 | 0.55 | 0.66 | 0.165 | 0.088 | 0.021 |
SD | 15.55 | 0.07 | 0.70 | 0.21 | 0.07 | 0.06 | 0.11 | 0.09 | 0.036 | 0.012 | 0.003 | |
180 (n = 10) | Mean | 242.5 | 2.01 | 7.41 | 1.59 | 0.77 | 0.38 | 0.63 | 0.88 | 0.154 | 0.085 | 0.022 |
SD | 14.74 | 0.11 | 0.62 | 0.14 | 0.05 | 0.05 | 0.10 | 0.28 | 0.027 | 0.018 | 0.006 | |
±% | 0 | 4 | 12 | −1 | −7 | −8 | 15 | 32 | −7 | −4 | 9 | |
SS | ∗ | ∗ | ||||||||||
300 (n = 8) | Mean | 250.4 | 1.98 | 7.07 | 1.56 | 0.92 | 0.33 | 0.61 | 0.58 | 0.148 | 0.092 | 0.022 |
SD | 15.97 | 0.08 | 0.56 | 0.09 | 0.09 | 0.05 | 0.06 | 0.18 | 0.034 | 0.016 | 0.004 | |
±% | 4 | 2 | 7 | −3 | 11 | −20 | 11 | −12 | −10 | 4 | 6 | |
SS | ∗ | ∗∗ | ||||||||||
375 (n = 10) | Mean | 247.3 | 1.96 | 7.16 | 1.55 | 0.95 | 0.31 | 0.61 | 0.57 | 0.151 | 0.095 | 0.022 |
SD | 21.06 | 0.06 | 0.84 | 0.14 | 0.14 | 0.07 | 0.11 | 0.19 | 0.031 | 0.016 | 0.005 | |
±% | 2.2 | 0.7 | 8.0 | −3.5 | 14.7 | −25.0 | 11.1 | −13.2 | −8.3 | 6.9 | 8.3 | |
SS |
±%, percent deviation versus control, mg/kg bw/d, milligrams per kilogram body weight per day; SD, standard deviation; g, grams; SS, statistical significance; n, number of animals.
∗ p < 0.05; ∗∗ p < 0.01.