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. 2016 Aug 30;57(6):1361–1369. doi: 10.3349/ymj.2016.57.6.1361

Table 2. A Multivariate Analysis Predicting 28-Day Mortality in Septic Patients from the Training Set.

Model 1 (AUC: 0.7901) Model 2 (AUC: 0.7901) Model 3 (AUC: 0.8173) Model 4 (AUC: 0.8173)
OR (95% CI) p value OR (95% CI) p value OR (95% CI) p value OR (95% CI) p value
Albumin 0.276 (0.178–0.427) <0.001 0.276 (0.178–0.427) <0.001 0.254 (0.161–0.403) <0.001 0.254 (0.161–0.403) <0.001
BE 0.899 (0.856–0.944) <0.001 0.899 (0.856–0.944) <0.001 0.901 (0.856–0.948) <0.001 0.901 (0.856–0.948) <0.001
RR 1.119 (1.057–1.183) <0.001 1.119 (1.057–1.183) <0.001

AUC, area under the receiver operating characteristic curve; OR, odds ratio; CI, confidence interval; BE, base excess; RR, respiratory rate; APACHE II, Acute Physiology and Chronic Health Evaluation II; SOFA, Sepsis Organ Failure Assessment; NEWS, National Early Warning Score.

Each scoring system was entered individually into the multivariate logistic regression analysis with clinical variables and laboratory variables in the training set. A total of four models were generated by a stepwise multivariate analysis method. Model 1 includes clinical variables, laboratory variables, and APACHE II; Model 2 includes clinical variables, laboratory variables, and NEWS; Model 3 includes clinical variables, laboratory variables, and SOFA; and Model 4 includes clinical variables and laboratory variables without a scoring system.