Table 1. Clinical and Biochemical Characteristics of Subjects.
| PCOS (n=450) | Control (n=450) | p value | |
|---|---|---|---|
| Age (yr) | 24±5 | 24±4 | 0.414 |
| BMI (kg/m2) | 22.9±3.5 | 22.5±2.7 | 0.063 |
| WC (cm) | 77±9 | 75±7 | 0.007 |
| Percentage of fat (%) | 34±6 | 34±5 | 0.442 |
| Fat mass (kg) | 21±7 | 20±5 | 0.094 |
| SBP (mm Hg) | 110±10 | 107±9 | 0.001 |
| DBP (mm Hg) | 71±8 | 70±8 | 0.016 |
| TG (mg/dL) | 78 (58, 110) | 67 (52, 91) | <0.001 |
| HDL-C (mg/dL) | 51±14 | 49±11 | 0.017 |
| TG/HDL-C ratio | 1.5 (1.0, 2.6) | 1.4 (1.0, 2.0) | <0.001 |
| FPG (mg/dL) | 86±14 | 85±7 | 0.643 |
| 2-h PPG (mg/dL) | 108±35 | 96±18 | <0.001 |
| FPI (µU/mL) | 8.3 (6.0, 11.1) | 4.1 (0.2, 7.1) | <0.001 |
| 2-h PPI (µU/mL) | 45.9 (26.4, 80.5) | 22.1 (12.8, 37.7) | <0.001 |
| HOMA-IR | 1.7 (1.2, 2.4) | 0.8 (0.1, 1.5) | <0.001 |
| ISIest (µmol·kg−1·min−1·pmol/L−1) | 0.09 (0.07, 0.10) | 0.11 (0.10, 0.12) | <0.001 |
| HOMA-β (%) | 145.4 (90.3, 222.7) | 58.5 (3.5, 119.6) | <0.001 |
| Total testosterone (ng/dL) | 76±18 | 46±16 | <0.001 |
| SHBG (nmol/L) | 48.5±22.8 | 99.1± 57.6 | <0.001 |
| Free testosterone (ng/dL) | 1.1±0.4 | 0.4±0.2 | <0.001 |
PCOS, polycystic ovary syndrome; BMI, body mass index; WC, waist circumference; SBP, systolic blood pressure; DBP, diastolic blood pressure; TG, triglycerides; HDL-C, high-density lipoprotein cholesterol; FPG, fasting plasma glucose; 2-h PPG, 2-h postload plasma glucose; FPI, fasting plasma insulin; 2-h PPI, 2-h postload plasma insulin; HOMA-IR, homeostasis model assessment of insulin resistance; ISIest, estimated insulin sensitivity index; HOMA-β, homeostasis model assessment of beta cell function; SHBG, sex hormone-binding globulin.
Data are means±SD. Values before parentheses are medians, and values in parentheses are interquartile ranges. TG, TG/HDL-C ratio, FPI, 2-h PPI, HOMA-IR, and ISI were analyzed after log transformation.