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. 2016 Aug 30;57(6):1454–1460. doi: 10.3349/ymj.2016.57.6.1454

Table 3. OR for New-Onset Hypertension According to Baseline UACR Tertile.

UACR at baseline
Tertile 1 Tertile 2 Tertile 3 P for trend
Men
 UACR, mg/g <5.38 5.38–9.36 ≥9.37
 No. of subjects 147 147 148
 No. of new-onset hypertension 14 (9.5%) 20 (13.6%) 23 (15.5%)
 OR (95% CI) for new-onset hypertension
  Model 1 1.00 1.47 (0.71–3.04) 1.71 (0.84–3.48) 0.146
  Model 2 1.00 1.58 (0.75–3.33) 1.66 (0.79–3.48) 0.187
  Model 3 1.00 1.65 (0.78–3.50) 1.83 (0.85–3.94) 0.124
Women
 UACR, mg/g <6.17 6.17–11.63 ≥11.64
 No. of subjects 243 244 244
 No. of new-onset hypertension 11 (4.5%) 24 (9.8%) 31 (12.7%)
 OR (95% CI) for new-onset hypertension
  Model 1 1.00 2.20 (1.05–4.64) 2.62 (1.27–5.40) 0.008
  Model 2 1.00 2.59 (1.20–5.57) 2.73 (1.29–5.78) 0.012
  Model 3 1.00 2.57 (1.19–5.56) 2.69 (1.27–5.73) 0.014

UACR, urine albumin-to-creatinine ratio; OR, odds ratio; CI, confidence interval; BMI, body mass index; HDL, high-density lipoprotein; hs-CRP, high-sensitivity C-reactive protein; GFR, glomerular filtration rate.

Model 1: adjusted for age, Model 2: Model 1+additionally adjusted for baseline BMI, muscle mass, systolic blood pressure, diabetes mellitus, smoking, alcohol consumption, regular exercise, Model 3: Model 2+additionally adjusted for baseline fasting serum glucose, triglyceride, HDL cholesterol, hs-CRP, estimated GFR.