Table 3. OR for New-Onset Hypertension According to Baseline UACR Tertile.
UACR at baseline | ||||
---|---|---|---|---|
Tertile 1 | Tertile 2 | Tertile 3 | P for trend | |
Men | ||||
UACR, mg/g | <5.38 | 5.38–9.36 | ≥9.37 | |
No. of subjects | 147 | 147 | 148 | |
No. of new-onset hypertension | 14 (9.5%) | 20 (13.6%) | 23 (15.5%) | |
OR (95% CI) for new-onset hypertension | ||||
Model 1 | 1.00 | 1.47 (0.71–3.04) | 1.71 (0.84–3.48) | 0.146 |
Model 2 | 1.00 | 1.58 (0.75–3.33) | 1.66 (0.79–3.48) | 0.187 |
Model 3 | 1.00 | 1.65 (0.78–3.50) | 1.83 (0.85–3.94) | 0.124 |
Women | ||||
UACR, mg/g | <6.17 | 6.17–11.63 | ≥11.64 | |
No. of subjects | 243 | 244 | 244 | |
No. of new-onset hypertension | 11 (4.5%) | 24 (9.8%) | 31 (12.7%) | |
OR (95% CI) for new-onset hypertension | ||||
Model 1 | 1.00 | 2.20 (1.05–4.64) | 2.62 (1.27–5.40) | 0.008 |
Model 2 | 1.00 | 2.59 (1.20–5.57) | 2.73 (1.29–5.78) | 0.012 |
Model 3 | 1.00 | 2.57 (1.19–5.56) | 2.69 (1.27–5.73) | 0.014 |
UACR, urine albumin-to-creatinine ratio; OR, odds ratio; CI, confidence interval; BMI, body mass index; HDL, high-density lipoprotein; hs-CRP, high-sensitivity C-reactive protein; GFR, glomerular filtration rate.
Model 1: adjusted for age, Model 2: Model 1+additionally adjusted for baseline BMI, muscle mass, systolic blood pressure, diabetes mellitus, smoking, alcohol consumption, regular exercise, Model 3: Model 2+additionally adjusted for baseline fasting serum glucose, triglyceride, HDL cholesterol, hs-CRP, estimated GFR.