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. 2016 Aug 24;18(3):371–380. doi: 10.22074/cellj.2016.4565

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Fig.1 — Expression of miR-223 and the percentage of Th17 and regulatory T (Treg) cells in CD4⁺T-cells. A. miR-223 significantly upregulated in the relapsing phase of relapsing-remitting multiple sclerosis (RR-MS). There was no significant difference between the remitting phase and healthy subjects, B and C. Flow cytometry results revealed an increased percentage of Th17 cells [RAR-related Orphan Receptor γt (RORγt)] in the relapsing phase.

In the remitting phase, there was an elevated percentage of Treg cells [FORKHEAD BOX P3 (FOXP3)]. *; P<0.05, **; P<0.01, and ***; P<0.005, non-parametric Mann-Whitney t test.