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. 2016 Sep 5;4(1):22. doi: 10.1186/s40349-016-0066-7

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© The Author(s) 2016

Open Access This article is distributed under the terms of the Creative Commons Attribution 4.0 International License(http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver(http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Fig. 1 — Open-source small-animal MRgFUS system overview. The delivery table holds the target and transducer at magnet isocenter while imaging is performed. Therapy control software for planning and closed-loop temperature control is implemented in Matlab on the MRI scanner’s host PC, which collects the real-time MR images, computes the focal temperature, and modulates the ultrasound output accordingly