Figure 4.

Flow cytometric analysis of cytotoxic T lymphocyte antigen (CTLA)−4 expression in CD4⁺ T cells. Flow cytometric comparison of CTLA‐4 expression in the (a) CD4⁺CD25^–, (b) CD4⁺CD25^int and (c) CD4⁺CD25^hi T cell populations in latent autoimmune diabetes of adults (LADA) (n = 37) and healthy control individuals (n = 20). Flow cytometric comparison of the percentage of CTLA‐4 forkhead box protein 3 (FoxP3)⁺ T cells among (d) CD4⁺CD25^–, (e) CD4⁺CD25^int and (f) CD4⁺CD25^hi T cell populations in LADA patients (n = 37) and healthy control individuals (n = 20). Mean value for each group is indicated with a horizontal line.