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. 2016 Jul 28;186(1):30–38. doi: 10.1111/cei.12826

Figure 6.

Figure 6

CD68 macrophages expressing H‐ferritin in skin infiltrate of adult‐onset Still's disease (AOSD) patients. Haematoxylin and eosin staining of AOSD patients (a) and healthy controls (HCs) (c). In AOSD patients, an infiltrate enriched in monocytes/macrophages cells may be observed. Only few neutrophils and eosinophils may be detected. The immunofluorescence analysis shows: (b) a large number of CD68+/H‐ferritin+ cells may be identified in the skin of AOSD patients; conversely, (d) only one CD68+/H‐ferritin+ cell may be observed in the skin of HCs. (e) A significantly increased number of CD68+/H‐ferritin+ cells is present in AOSD skin when compared to HCs (***P < 0·001). (f) A positive correlation between CD68+/H‐ferritin+ cells and the Pouchot's score was observed.