Fig. (3).

A psychobehavioral basis of integrating pleiotropic natural product into the network pharmacology in which the compound becomes both an incentive and an active ingredient of the combination therapy. (A) - External incentives are tested to support medication adherence [134]. (B) – A new concept of combining a pharmaceutical drug with a specific natural product which becomes pharmacologically-active incentive. (C) Having a choice as a psychobehavioral incentive targeting an intrinsic motivation of a patient. Shared-decision making and daily self-administration of natural product support self-care.