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. Author manuscript; available in PMC: 2016 Oct 1.
Published in final edited form as: J Pathol. 2015 Jul 29;237(2):166–178. doi: 10.1002/path.4566

Figure 3. Non-synonymous somatic mutations detected by targeted capture massively parallel sequencing in acinic cell carcinomas of the breast.

Figure 3

Heatmap indicating the non-synonymous somatic mutations considered not to be neutral by either MutationTaster or CHASM. Cases are represented in columns; genes are depicted in rows. Mutation types are color-coded according to the legend. The presence of loss of heterozygosity of the wild-type allele in association with the somatic mutation is depicted by a diagonal bar. On the right, the membership of each gene in three cancer gene datasets, Kandoth et al. [41], Cancer Gene Census [42] and Lawrence et al. [43], is reported. ACC, acinic cell carcinoma; CC, clear cell focus; G1=grade 1; G2=grade 2.