Table 1.
Case | Age/gender diagnosis |
Prior failed therapies | Concomitant medications | Comorbid conditions |
---|---|---|---|---|
1 | 70/F Amyopathic DM |
Prednisone (up to 60 mg/day) MMF (1000 mg bid) AZA (100 mg qd) CYC (100 mg bid) Etanercept (50 mg) Infliximab (5 mg/kg) IVIg (2 g/kg) Adalimumab (40 mg) Thalidomide (100 mg qd) MTX (15 mg) Hydroxychloroquine (200 mg bid) Quinacrine (100 mg) Ustekinumab (45 mg) |
Rituximab (1000 mg) Prednisone (5 mg/day with tapering off) |
|
| ||||
2 | 50/M DM |
Prednisone (up to 60 mg/day) AZA (50 mg bid) |
Prednisone (30 mg/day with tapering) AZA (200 mg/day) IVIg (2 g/kg) MTX (20 mg) |
|
| ||||
3 | 52/F PM |
Prednisone (up to 20 mg/day) MMF (1000 mg bid) |
Prednisone (20 mg/day with tapering to 5 mg) MMF (2000 mg bid) |
ILD Sjögren's syndrome Primary biliary cirrhosis Diabetes |
| ||||
4 | 57/M PM Anti-SRP antibody positive |
IV steroids (1 g/day for 3 days) Prednisone (up to 60 mg/day) IVIg (2 g/kg) AZA (50 mg bid) Rituximab (1000 mg) |
Prednisone (10 mg/day with tapering off) | Hepatitis C Hypertension Hyperlipidemia |
MMF: mycophenolate mofetil; AZA: azathioprine; CYC: cyclosporine; MTX: methotrexate; ILD: interstitial lung disease.