Table 3.
Statistical significance of differences in all-cause mortality evaluated by the Kaplan-Meier analysis for vitamin D signaling pathway genes and CASR in hemodialysis patients undergoing the 7-year prospective study.
| Tested polymorphism | N | Major homozygotes versus heterozygotes versus minor homozygotesa | Dominant model of inheritanceb | Recessive model of inheritanceb | Additive model of inheritanceb |
|---|---|---|---|---|---|
| GC rs7041 | 458 | GG versus GT versus TT P = 0.692 |
TT + GT versus GG P = 0.822 |
TT versus GT + GG P = 0.320 |
TT versus GG P = 0.427 |
| GC rs1155563 | 472 | TT versus CT versus CC P = 0.342 |
CC + CT versus TT P = 0.420 |
CC versus CT + TT P = 0.275 |
CC versus TT P = 0.255 |
| GC rs2298849 | 472 | TT versus CT versus CC P = 0.136 |
CC + CT versus TT P = 0.024 |
CC versus CT + TT P = 0.829 |
CC versus TT P = 0.559 |
| RXRA rs10881578 | 472 | AA versus AG versus GG P = 0.252 |
GG + AG versus AA P = 0.151 |
GG versus AG + AA P = 0.587 |
GG versus AA P = 0.404 |
| RXRA rs10776909 | 472 | CC versus CT versus TT P = 0.848 |
TT + CT versus CC P = 0.672 |
TT versus CT + CC P = 0.908 |
TT versus CC P = 0.876 |
| RXRA rs749759 | 464 | GG versus AG versus AA P = 0.516 |
AA + AG versus GG P = 0.263 |
AA versus AG + GG P = 0.942 |
AA versus GG P = 0.830 |
| VDR rs1544410 | 461 | GG versus AG versus AA P = 0.555 |
AA + AG versus GG P = 0.372 |
AA versus AG + GG P = 0.471 |
AA versus GG P = 0.348 |
| VDR rs2228570 | 449 | CC versus CT versus TT P = 0.863 |
TT + CT versus CC P = 0.677 |
TT versus CT + CC P = 0.470 |
TT versus CC P = 0.493 |
| CASR rs7652589 | 435 | GG versus AG versus AA P = 0.255 |
AA + AG versus GG P = 0.200 |
AA versus AG + GG P = 0.352 |
AA versus GG P = 0.209 |
CASR: calcium-sensing receptor gene, GC: group-specific component gene, RXRA: retinoic X receptor alpha gene, and VDR: vitamin D receptor gene.
aMultiple-sample test P.
bLog rank test P.