Table 2.
MIC interpretation of five antifungal drugs against Candida spp. recovered from endotracheal tube.
| Antifungal agents |
C. albicans
n = 34 (%) |
C. glabrata
n = 24 (%) |
C. parapsilosis
n = 16 (%) |
C. tropicalis
n = 12 (%) |
C. krusei
n = 9 (%) |
|
|---|---|---|---|---|---|---|
| Amphotericin B | S | 28 (82.3) | 20 (83.3) | 16 (100) | 10 (83.3) | 7 (77.7) |
| R | 6 (17.6) | 4 (16.6) | — | 2 (16.7) | 2 (22.2) | |
|
| ||||||
| Itraconazole | S | 20 (58.8) | 12 (50) | 6 (37.5) | 4 (33.3) | 3 (33.3) |
| DD | 2 (5.8) | 6 (25) | 10 (62.5) | — | 5 (55.5) | |
| R | 12 (35.2) | 6 (25) | — | 8 (66.6) | 1 (11.1) | |
|
| ||||||
| Voriconazole | S | 27 (79.4) | 11 (45.8) | 12 (75) | 4 (33.3) | 6 (66.6) |
| DD | 2 (5.8) | 5 (20.8) | 4 (25) | 3 (25) | 2 (22.2) | |
| R | 5 (14.7) | 8 (33.3) | — | 5 (41.6) | 1 (11.1) | |
|
| ||||||
| Fluconazole | S | 22 (64.7) | 3 (12.5) | 14 (87.5) | 3 (25) | 5 (55.5) |
| DD | 3 (8.8) | 2 (8.3) | 2 (12.5) | 4 (33.3) | 2 (22.2) | |
| R | 9 (26.4) | 19 (79.1) | — | 5 (41.6) | 2 (22.2) | |
|
| ||||||
| Caspofungin | S | 34 (100) | 24 (100) | 16 (100) | 12 (100) | 9 (100) |
| R | — | — | — | — | — | |
S: susceptible; R: resistance; DD: dose-dependent.