Table I.
Study (first author, year) | N | Age [years] | Anemia definition, hemoglobin level [g/dl] | ESA therapy | Follow-up [months] | ||
---|---|---|---|---|---|---|---|
ESA | Control | ESA | Control | ||||
Cleland, 2005 | 24 | 69 | 74 | < 12.5 | DA | Placebo | 2 |
Ghali, 2008 | 319 | 68 | 69 | 9–12 | DA + iron | Placebo + iron | 12 |
Kaurea, 2008 | 41 | 73 | 65 | < 12.5 | DA + iron | Placebo + iron | 3 |
Mancini, 2003 | 23 | 87 | 63 | Hematocrit < 35% | EPO + iron | Placebo + iron | 3 |
Palazzuoli, 2006 | 38 | 72 | 75 | < 11 | EPO + iron | Placebo + iron | 9 |
Palazzuoli, 2007 | 51 | 74 | 72 | < 11.5 | EPO + iron | Placebo + iron | 8 |
Parissis, 2008 | 32 | 72 | 69 | < 12.5 | DA + iron | Placebo + iron | 3 |
Ponikowski, 2007 | 41 | 70 | 72 | 9–12 | DA + iron | Placebo + iron | 6 |
Silverberg, 2001 | 32 | 75 | 72 | 10–11.5 | EPO + iron | Iron | 8 |
Swedberg, 2013 | 2278 | 71 | 72 | 9–12 | DA + iron | Placebo + iron | 28 |
Veldhuisen, 2007 | 165 | 71 | 71 | 9–12 | DA + iron | Placebo + iron | 6 |
EPO – erythropoietin, DA – darbepoetin alfa, ESA – erythropoiesis-stimulating agent.