FIG. 3.

Heat map of differential gene expression among athletes before (baseline) and after (acute and sub-acute) sports-related concussion (SRC). Color-coded expression levels of the 766 probesets that were significantly changed post-SRC (acute and sub-acute) relative to baseline (X-axis) among 16 SRC athletes, standardized to mean 0 and standard deviation of 1. Up-regulated genes are red, down-regulated genes are blue, genes with unchanged expression are colored gray. Individual SRC athletes are along the Y-axis, and grouped by the three indicated time-points. (There are fewer subjects at the acute time-point because of inadequate RNA in six peripheral blood mononuclear cell samples). A heat map of differential gene expression among uninjured athlete controls was not displayed because no significant pre-post changes in gene expression were detected. Color image is available online at www.liebertpub.com/neu