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. 2016 Sep 1;33(17):1586–1597. doi: 10.1089/neu.2015.4261

Table 6.

Studies on Cranioplasty and Brain Perfusion

Author Year Number of patients Modality Conclusion
Suzuki and colleagues 1993 6 PCT ↑ 2 and 20% in defect and healthy sides
Maekawa and colleagues 1999 8 Xe-CT ↑ In 4 out 8 defect and 3 out 8 healthy sides
Winkler and colleagues 2000 13 PET scan ↑ glucose intake by 12% in defect and by 4% in healthy sides
Agner and colleagues 2002 1 Xe-CT ↑ 125% after surgery
Isago and colleagues 2004 1 Xe-CT ↑ 2-fold and 1.5-fold on each side
Sakamoto and colleagues 2006 1 PCT ↑ From 23.1 to 37.4 mL/100 g/sec and from 31.8 to 41.6 mL/100 g/sec in the defect and healthy sides, respectively
Won and colleagues 2008 27 PCT ↑ From 39.1 to 44.7 mL/100 g/sec and from 42.9 to 47.2 mL/100 g/sec in the defect and healthy sides, respectively.
Decaminada and colleagues 2008 10 PCT Slight ↑ in ` in defect side
Kemmling and colleagues 2010 1 PMR ↑ of CBV and CBF. and ↓ MTT defect after surgery
Sarubbo and colleagues 2014 6 PCT ↑ in CBV and CBF. and ↓ in TTP in defect side at 7 days
Paredes and colleagues 2015 49 PCT ↑ From 101.86 to 117.17 mL/100 g/sec and from 128.14 to 145.73 mL/100 g/sec in the defect and healthy sides, respectively

PCT, perfusion computed tomography; Xe-CT, Xenon-enhanced computed tomography; PET, positron emission tomography; CBV, cerebral blood volume; CBF cerebral blood flow; TTP, time to peak; PMR, perfusion magnetic resonance.