Table 1.
Twenty-four up-regulated and 17 down-regulated genes in gastric cancer cells from malignant ascites compared with those from primary lesions
| Gene expression level | Gene name | Gene function |
| Down-regulated | ||
| Nucleobinding 2 | Signaling (apoptosis) | |
| Acyl-Coenzyme A dehydrogenase | Signaling | |
| Chaperonin containing TCP1 | Signaling | |
| FKBP54 | Signaling | |
| Histone deacetylase 3 | Signaling | |
| p27kip | Signaling | |
| PAK-interacting exchange factor alpha | Signaling | |
| CD4 | Immune response | |
| IL4 stat | Immune response | |
| L2 receptor gamma | Immune response | |
| IGFBP2 | Growth and metabolism | |
| RAD51 homologue C | Chromosome stability | |
| Heterogenous nuclear ribonucleoprotein | Cell adhesion | |
| Integrin β4 | Cell adhesion | |
| Tubulin beta-1 chain | Cell adhesion | |
| Death associated protein | Apoptosis | |
| H2A histone family member L | Apoptosis | |
| Up-regulated | ||
| Dopa decarboxylase | Signaling or progression | |
| Caveolin-3 | Signaling (modification) | |
| CD9 | Signaling | |
| Dystroglycan1 | Signaling | |
| Inositol triphosphate receptor | Signaling | |
| LMO 7 | Signaling | |
| Sodium/hydrogen exchanger, isoform 1 | Signaling | |
| Cystein protease (legumain) | Invasion | |
| Myosin 6 | Intracellular organelle transport | |
| Destrin (actin depolymerising factor) | Interaction with extracellular matrix | |
| Renal tumor antigen RAGE1 | Immune response | |
| Aldehyde dehydrogenase | Drug metabolism | |
| Aldo-keto reductase family 1 | Drug metabolism | |
| Keratin 14 | Cell adhesion, invasion | |
| Keratin 7 | Cell adhesion, invasion | |
| Keratin 8 | Cell adhesion, invasion | |
| CD44 | Cell adhesion | |
| Desmoplakin (DPI, DPII) | Cell adhesion | |
| Galectin 3 (lectin) | Cell adhesion | |
| Integrin alpha3 | Cell adhesion | |
| Occludin | Cell adhesion | |
| S100 A10 (ligand of Annexin II) | Cell adhesion | |
| Leukocyte elastase inhibitor | Apoptosis | |
| TGFb-induced anti-apoptotic factor | Apoptosis |