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. 2016 Aug 10;149(2):139–145. doi: 10.1111/imm.12646

Table 1.

Examples of post‐translational modifications (PTMs) monitored by MHC class I molecules

PTMs Sites of modifications Crystallized MHC class I alleles References
Phosphorylation Ser, Thr HLA‐A2 10, 16, 17
O‐linked glycosylation Ser, Thr H‐2Kb 11, 12, 18, 20
Acetylation N terminus HLA‐B39 24, 56
Formylation N terminus H2‐M3 45, 57
N‐myristoylation N‐terminal Gly Mamu‐B*098 6, 7, 8
Citrullination Arg HLA‐B27 22, 58
Methylation Arg Not reported 59
Deamidation Asn Not reported 60
Cysteinylation Cys Not reported 61