Table 7. Target genes for the first 10 down-regulated boar sperm miRNAs in both comparison groups are shown, using target mining selection of miRDB (http://mirdb.org/miRDB/mining.html).
| miRNA | Gene symbol | Gene description | Target score |
|---|---|---|---|
| hsa-miR-196a-5p | ZMYND11 | zinc finger, MYND-type containing 11 | 100 |
| hsa-miR-196a-5p | SLC9A6 | solute carrier family 9, subfamily A (NHE6, cation proton antiporter 6), member 6 | 100 |
| hsa-miR-196a-5p | AQP4 | aquaporin 4 | 98 |
| hsa-miR-514a-3p | EGFR | epidermal growth factor receptor | 98 |
| hsa-miR-514a-3p | CABLES1 | Cdk5 and Abl enzyme substrate 1 | 98 |
| hsa-miR-196a-5p | HOXB7 | homeobox B7 | 97 |
| hsa-miR-514a-3p | AGO4 | argonaute RISC catalytic component 4 | 97 |
| hsa-miR-196a-5p | NR2C2 | nuclear receptor subfamily 2, group C, member 2 | 97 |
| hsa-miR-514a-3p | ECE1 | endothelin converting enzyme 1 | 97 |
| hsa-miR-196a-5p | GATA6 | GATA binding protein 6 | 96 |
| hsa-miR-514a-3p | NCOA7 | nuclear receptor coactivator 7 | 96 |
| hsa-miR-514a-3p | PTEN | phosphatase and tensin homolog | 96 |
| hsa-miR-196a-5p | PBX1 | pre-B-cell leukemia homeobox 1 | 96 |
| hsa-miR-514a-3p | QSER1 | glutamine and serine rich 1 | 95 |
| hsa-miR-196a-5p | ERI2 | ERI1 exoribonuclease family member 2 | 95 |
| hsa-miR-514a-3p | JAM2 | junctional adhesion molecule 2 | 95 |
| hsa-miR-514a-3p | C7 | complement component 7 | 95 |
| hsa-miR-196a-5p | DENND6A | DENN/MADD domain containing 6A | 94 |
| hsa-miR-196a-5p | CCDC47 | coiled-coil domain containing 47 | 94 |
| hsa-miR-514a-3p | BAALC | brain and acute leukemia, cytoplasmic | 94 |
| hsa-miR-196a-5p | RDX | Radixin | 94 |
| hsa-miR-196a-5p | MAP3K1 | mitogen-activated protein kinase kinase kinase 1, E3 ubiquitin protein ligase | 94 |
| hsa-miR-514a-3p | TMEM68 | transmembrane protein 68 | 94 |
| hsa-miR-514a-3p | SLC39A9 | solute carrier family 39, member 9 | 94 |
| hsa-miR-196a-5p | HOXC8 | homeobox C8 | 94 |
| hsa-miR-196a-5p | CEP350 | centrosomal protein 350kDa | 93 |
| hsa-miR-514a-3p | SPTLC3 | serine palmitoyltransferase, long chain base subunit 3 | 93 |
| hsa-miR-514a-3p | AFF4 | AF4/FMR2 family, member 4 | 93 |
| hsa-miR-514a-3p | PTPRG | protein tyrosine phosphatase, receptor type, G | 93 |
| hsa-miR-196a-5p | ELAVL4 | ELAV like neuron-specific RNA binding protein 4 | 93 |
| hsa-miR-514a-3p | COL2A1 | collagen, type II, alpha 1 | 93 |
| hsa-miR-196a-5p | ABCB9 | ATP-binding cassette, sub-family B (MDR/TAP), member 9 | 93 |
| hsa-miR-514a-3p | TCF12 | transcription factor 12 | 92 |
| hsa-miR-196a-5p | RCC2 | regulator of chromosome condensation 2 | 92 |
| hsa-miR-196a-5p | HOXA7 | homeobox A7 | 92 |
| hsa-miR-514a-3p | SYT11 | synaptotagmin XI | 92 |
| hsa-miR-196a-5p | NTN4 | netrin 4 | 92 |
| hsa-miR-196a-5p | HOXA5 | homeobox A5 | 92 |
| hsa-miR-514a-3p | ZNF282 | zinc finger protein 282 | 91 |
| hsa-miR-514a-3p | USP27X | ubiquitin specific peptidase 27, X-linked | 91 |
| hsa-miR-514a-3p | FAM117A | family with sequence similarity 117, member A | 91 |
| hsa-miR-196a-5p | CCNJ | cyclin J | 91 |
| hsa-miR-514a-3p | ZNF800 | zinc finger protein 800 | 91 |
| hsa-miR-196a-5p | NR6A1 | nuclear receptor subfamily 6, group A, member 1 | 91 |
| hsa-miR-514a-3p | PLCL1 | phospholipase C-like 1 | 91 |
| hsa-miR-196a-5p | SMC3 | structural maintenance of chromosomes 3 | 90 |
| hsa-miR-196a-5p | LARP4 | La ribonucleoprotein domain family, member 4 | 90 |
| hsa-miR-196a-5p | TSTD3 | thiosulfate sulfurtransferase (rhodanese)-like domain containing 3 | 90 |
| hsa-miR-196a-5p | LRIG3 | leucine-rich repeats and immunoglobulin-like domains 3 | 90 |
| hsa-miR-514a-3p | PPP2R1A | protein phosphatase 2, regulatory subunit A, alpha | 90 |
| hsa-miR-196a-5p | PACRGL | PARK2 co-regulated-like | 90 |
| hsa-miR-196a-5p | ZNF850 | zinc finger protein 850 | 90 |
| hsa-miR-196a-5p | TMX1 | thioredoxin-related transmembrane protein 1 | 90 |
| hsa-miR-196a-5p | LIX1L | Lix1 homolog (mouse)-like | 90 |
| hsa-miR-514a-3p | PCCA | propionyl CoA carboxylase, alpha polypeptide | 90 |
| hsa-miR-514a-3p | AKAP10 | A kinase (PRKA) anchor protein 10 | 90 |
| hsa-miR-514a-3p | NCOR1 | nuclear receptor corepressor 1 | 90 |
| hsa-miR-196a-5p | LRIG2 | leucine-rich repeats and immunoglobulin-like domains 2 | 90 |
| hsa-miR-196a-5p | RET | ret proto-oncogene | 90 |
Only functional miRNAs were included. MiRNAs with >300 predicted targets in genome were excluded, whereas target genes with ≥ 90 target score were shown.