Table 2. Expression of miRNAs in cancer and precancer.
miRNA | Expression in fold change |
|||
---|---|---|---|---|
Cancer (n = 23) | Leukoplakia (n = 18) | Lichen planus (n = 12) | Oral submucous fibrosis (n = 23) | |
hsa-miR-7 | 2 ↑* | 6 ↑* | 14 ↑* | 1 |
hsa-miR-31 | 30 ↑* | 68 ↑* | 19 ↑* | 3 ↑* |
hsa-miR-31* | 41 ↑* | 65 ↑* | 182 ↑* | 2 ↑ |
hsa-miR-133a | 209 ↓* | 20 ↑* | 1 | 3 ↑ |
hsa-miR-204 | 23 ↓* | 4 ↑ | 3 ↑* | 8 ↓* |
hsa-miR-206 | 126 ↓* | 22 ↑* | 3 ↑ | 2 ↑ |
hsa-miR-1293 | 5 ↑* | 33 ↑* | 6 ↑* | 1 |
Expression in fold change of miRNAs in cancer and pre-cancer tissues were calculated with respect to the normal oral tissues from healthy individuals.
*Significant after independent t-test with P value < 0.05 and Benjamini-Hochberg multiple testing correction.
↑: upregulation; ↓: downregulation of expression.