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. 2016 Sep 6;6:32972. doi: 10.1038/srep32972

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Copyright © 2016, The Author(s)

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(A,B) Apoptosis assays demonstrated that an up regulation of miR-370-3p increased TMZ-induced cell death in the LN18 cells (*P < 0.05). (C) The mean number of foci per cell for various doses is shown. Number differences of foci in groups were labelled with asterisks. Error bars represent SEMs. (D) γ-H2AX foci (green) in non-chemotherapy treatment (a–d) and miR-370-3p treatment cells (e–h) followed different TMZ doses (0 μM, 1 μM, 5 μM, 10 μM); nuclei were stained with 4,6-diamidino-2-phenylindole (blue). Data represents the mean of three independent experiments; bars: SEMs.