Figure 2. Summary of molecular dynamics simulations.

Sequence of phase segregation for different MD simulations. Voronoi polygons are filled with a colour corresponding to each lipid component: unsaturated lipid (DUPC in blue), saturated lipid (red) and cholesterol (orange). Upper and lower rows correspond to each membrane leaflet. (a) Ternary system with a short-tailed saturated lipid (DLPC) resulting in domain registration. (b) Ternary system with a long-tailed saturated lipid (DSPC) resulting in domain antiregistration. (c) Inclusion of chloroform to the DUPC/DSPC/Chol system leads to a registration of segregating domains, whereas chloroform removal recovers the antiregistration behavior.