Table 2.
Pairwise pol distance, env population distance and diversity along with infection stage of transmission pairs
| Pair | pol distance (%) | No. of env sequences | env distance (%) | env diversity (%) | Infection stage | |||
|---|---|---|---|---|---|---|---|---|
| T | R | T | R | T | R | |||
| T1–R1 | 0.24 | 28 | 23 | 1.45 | 3.05 | 0.26 | Chronic | Acute |
| T2–R2 | 0.48 | 21 | 27 | 2.45 | 4.61 | 0.18 | Chronic | Acute |
| T3–R3 | 0.71 | 20 | 11 | 1.49 | 3.37 | 0.10 | Chronic | Acute |
| T4–R4 | 0.48 | 30 | 10 | 0.85 | 1.69 | 0.07 | Chronic | Acute |
| T5–R5 | 0.23 | 18 | 19 | 0.28 | 0.93 | 0.22 | Chronic | Acute |
| T6–R6 | 0.24 | 25 | 18 | 0.11 | 0.51 | 0.34 | Recent | Acute |
| T7–R7 | 0.15 | 5 | 18 | 0.12 | 0.34 | 0.12 | eART-STIb | Acute |
| T8–R8 | 0.08 | 17 | 19 | 0.32 | 0.50 | 0.11 | eART-STIb | Acute |
| T9–R9 | 0.16 | 5a | 8 | 1.40 | 1.08 | 0.35 | Recent | Acute |
T transmitter, R recipient
aSequences of T9 are derived from full-length env clones only after several SGA attempts failed
b Early antiretroviral treatment (eART) was started immediately after infection and HIV-1 was transmitted upon virus rebound after structured treatment interruption (STI)