Table 2.
Multivariate logistic regression analysis exploring association between quartiles of plasma lipid levels and the risk of MCI after adjustment for demographics, vascular disorders
| Lipid, Quartile (Range, mg/dl) | No. (%) of subjects | Basic Modela | Final Modelb | |
|---|---|---|---|---|
| MCI group (n = 112) | Control group (n = 115) | |||
| TC | ||||
| 1 (≤172.00) | 31 (27.7) | 28 (24.3) | 1.00 | 1.00 |
| 2 (172.01–197.00) | 33 (29.5) | 29 (25.2) | 1.52 (1.08–2.32) | 1.39 (1.07–2.11) |
| 3 (197.01–225.00) | 25 (22.3) | 27 (23.5) | 1.99 (1.47–2.81) | 1.79 (1.33–2.54) |
| 4 (≥225.01) | 23 (20.5) | 31 (27.0) | 2.72 (1.82–3.81) | 2.65 (2.13–3.39) |
| Trend test | P = 0.042 | P = 0.031 | ||
| HDL-C | ||||
| 1 (≤37.00) | 34 (30.3) | 27 (23.5) | 1.00 | 1.00 |
| 2 (37.01–45.00) | 22 (19.6) | 31 (27.0) | 0.62 (0.45–0.91) | 0.66 (0.41–1.08) |
| 3 (45.01–55.00) | 24 (21.4) | 28 (24.3) | 0.56 (0.45–0.97) | 0.61 (0.38–0.98) |
| 4 (≥55.01) | 32 (28.6) | 29 (25.2) | 0.48 (0.23–0.73) | 0.56 (0.37–0.83) |
| Trend test | P = 0.040 | P = 0.033 | ||
| TG | ||||
| 1 (≤98.25) | 33 (29.9) | 30 (26.1) | 1.00 | 1.00 |
| 2 (98.26–142.50) | 30 (26.6) | 28 (24.3) | 0.85 (0.57–1.27) | 0.95 (0.58–1.56) |
| 3 (142.51–197.50) | 25 (22.3) | 32 (27.8) | 0.82 (0.54–1.26) | 0.93 (0.58–1.50) |
| 4 (≥197.51) | 27 (24.1) | 25 (21.7) | 0.65 (0.43–0.91) | 0.76 (0.48–0.97) |
| Trend test | P = 0.047 | P = 0.039 | ||
| LDL-C | ||||
| 1 (≤98.25) | 33 (29.9) | 28 (24.3) | 1.00 | 1.00 |
| 2 (98.26–116.00) | 28 (25.0) | 31 (27.0) | 1.10 (0.74–1.66) | 0.87 (0.54–1.40) |
| 3 (116.01–141.75) | 27 (24.1) | 29 (25.2) | 0.91 (0.60–1.37) | 0.84 (0.52–1.35) |
| 4 (≥141.76) | 29 (25.9) | 27 (23.5) | 1.02 (0.68–1.53) | 1.02 (0.63–1.65) |
| Trend test | P =0.832 | P = 0.991 | ||
Data in the table are adjusted OR and 95 % CI
aAdjusted for potential confounders including age, gender, education level
bAdjusted for age, gender, education level, BMI, hypertension, T2DM, and heart disease