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. 2016 Sep 5;17(1):352. doi: 10.1186/s12859-016-1203-6

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© The Author(s) 2016

Open Access This article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver(http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Fig. 5 — Histogram of p-values in absence of enrichment in simulation S4. The test of Kolmogorov-Smirnov indicates that the distribution is uniform for NEAT (p=0.34), LA (p=0.11) and NP (p=0.32). The distribution of p-values is highly left-skewed for NEA, and right-skewed for LP