Table 10.
μ 0 | log10 (p-value) | ||||
---|---|---|---|---|---|
GO Slim BP set | NEAT | LA+S | NEAT | LA+S | |
1 | Response to oxidative stress | 242.2 | 248.5 | –202.7 | –253.7 |
2 | Carbohydrate metabolic process | 671.2 | 663.9 | –110.9 | –123.3 |
3 | Response to chemical stimulus | 885.1 | 912.4 | –83.4 | –92.8 |
4 | Oligosaccharide metabolic process | 165.3 | 158.1 | –77.3 | –104.5 |
5 | Cofactor metabolic process | 219.0 | 225.6 | –73.7 | –76.2 |
6 | Generation of precursor metabolites and energy | 294.8 | 293.4 | –54.0 | –56.1 |
7 | Nucleobase-containing small molecule metabolic process | 404.5 | 417.4 | –49.2 | –41.0 |
8 | Carbohydrate transport | 65.8 | 77.7 | –45.0 | –52.8 |
9 | Membrane invagination | 120.6 | 118.3 | –37.0 | –51.7 |
10 | Transmembrane transport | 644.4 | 684.7 | –24.2 | –16.2 |
11 | Protein folding | 296.9 | 296.3 | –22.7 | –26.6 |
12 | Lipid metabolic process | 484.4 | 495.7 | –19.9 | –23.3 |
13 | Endocytosis | 245.5 | 248.7 | –19.3 | –19.3 |
14 | Vacuole organization | 200.2 | 199.7 | –18.9 | –22.4 |
15 | Cellular respiration | 118.4 | 125.2 | –14.5 | –14.1 |
16 | Response to starvation | 331.4 | 318.4 | –11.2 | –15.8 |
17 | Protein targeting | 478.8 | 485.1 | –10.9 | –15.8 |
18 | Proteolysis involved in cellular protein catabolic process | 488.5 | 494.1 | –10.9 | –9.8 |
19 | Peroxisome organization | 124.8 | 123.5 | –6.0 | –6.0 |
20 | Lipid transport | 79.7 | 90.4 | –4.9 | –2.8 |
21 | Ion transport | 380.2 | 410.7 | –4.8 | –2.1 |
22 | Protein maturation | 27.7 | 30.9 | –3.9 | –3.0 |
23 | Cell morphogenesis | 79.4 | 80.8 | –3.6 | –3.7 |
24 | Sporulation | 306.4 | 301.7 | –2.1 | –2.5 |
25 | Amino acid transport | 109.4 | 113.0 | –2.1 | –1.6 |
26 | Response to osmotic stress | 181.8 | 178.3 | –1.6 | –2.1 |
27 | Protein phosphorylation | 587.6 | 564.3 | –1.4 | –2.7 |
The table reports the gene sets that are found to be over-enriched (α=1 %) by at least one of the two methods. μ 0 denotes the expected value of N AB in the absence of enrichment. The last two columns report log 10 p-values for the proposed NEAT and the LA+S test of [19], respectively