Table 2.
Relationships between the quartiles of HFABP and the incidence of AKI, levels of cardiac markers and in-hospital mortality
| Q1 | Q2 | Q3 | Q4 | ||
|---|---|---|---|---|---|
| H-FABP≦6.2 (n = 124) | 6.3≦H-FABP≦11.6 (n = 123) | 11.7≦H-FABP≦27.8 (n = 124) | 27.9≦H-FABP (n = 123) | p value | |
| Acute kidney injury | |||||
| no-AKI (yes, %) | 113 (91.1 %) | 102 (82.9 %) | 90 (72.6 %) | 44 (35.8 %) | <0.001 |
| Class R (yes, %) | 9 (7.3 %) | 16 (13.0 %) | 23 (18.5 %) | 35 (28.5 %) | <0.001 |
| Class I (yes, %) | 1 (0.8 %) | 5 (4.1 %) | 6 (4.8 %) | 24 (19.5 %) | <0.001 |
| Class F (yes, %) | 1 (0.8 %) | 0 (0.0 %) | 5 (4.0 %) | 20 (16.3 %) | <0.001 |
| Biomarkers | |||||
| hs-TropT (ng/ml) | 0.02 (0.01–0.03) | 0.04 (0.02–0.06) | 0.06 (0.03–0.10) | 0.14 (0.06–0.54) | <0.001 |
| Nt-proBNP (pg/ml) | 351 (68–1,748) | 2,401 (925–5,451) | 5,739 (1,991–13,267) | 7929 (2,164–23,269) | <0.001 |
| In-hospital mortality | |||||
| dead (yes, %) | 3 (2.4 %) | 5 (4.1 %) | 18 (14.5 %) | 38 (30.9 %) | <0.001 |
H-FABP heart-type fatty acid binding, LVEF left ventricular ejection fraction measured on echocardiography; WBC white blood cell; BUN blood urea nitrogen, BS blood sugar, CRP C-reactive protein, BNP brain natriuretic peptide, hs-TropT high-sensitivity troponin T, Nt-proBNP N-Terminal pro-brain-type natriuretic peptide, hs-CRP high-sensitivity C-reactive protein, NPPV noninvasive positive pressure ventilation, ETI endotracheal intubation, IABP intra-aortic balloon pumping, PCPS percutaneous cardiopulmonary support, CHDF continuous hemodiafiltration, ICU intensive care unit
p value between the quartiles of H-FABP determined using a variance analysis and the Kruskal-Wallis test