Table 3.

Multivariate analysis of the associations between acute kidney injury and the clinical findings

	AKI						Class I/F
	Univariate analysis			Multivariate analysis			Univariate analysis			Multivariate analysis
	OR	95 % CI	p value	OR	95 % CI	p value	OR	95 % CI	p value	OR	95 % CI	p value
Quartiles of H-FABP
Q1 (H-FABP≦6.2)	1.000			1.000			1.000			1.000
Q2 (6.3≦H-FABP≦11.6)	2.453	1.095– 5.498	0.029	3.743	1.693–8.274	0.001	2.585	0.492–13.584	0.262	3.194	0.582–17.523	0.181
Q3 (11.7≦H-FABP≦27.8)	5.030	2.311–10.947	<0.001	9.427	4.124–21.548	<0.001	5.938	1.288–27.374	0.022	5.155	1.030–25.790	0.046
Q4 (27.9≦H-FABP)	12.778	5.774 –28.777	<0.001	28.000	11.245–69.720	<0.001	33.975	8.009–144.122	<0.001	22.978	4.814 –109.668	<0.001
Adjusting Factors
Chronic kidney disease	1.196	0.786–1.819	0.404				0.652	0.373–1.141	0.134
Age (≧71 years old)	0.921	0.626–1.356	0.677				0.887	0.520–1.512	0.659
MBP (≧102 mmHg)	0.260	0.171–0.393	<0.001	0.264	0.172–0.442	<0.001	0.140	0.067–0.290	<0.001	0.191	0.087–0.416	<0.001
LVEF (≧51 %)	0.757	0.493–1.163	0.204				0.533	0.486–1.453	0.840
Hemoglobin (≧12.7 g/dl)	0.681	0.461–1.006	0.053				0.259	0.138–0.483	<0.001	0.430	0.212–0.874	0.020
Hs-TropT (≧0.048 ng/ml)	2.319	1.555–3.458	<0.001	0.736	0.428–1.265	0.267	4.035	2.160–7.536	<0.001	1.220	0.553–2.691	0.623
Nt-ProBNP (≧2553 pg/ml)	1.665	1.126–2.462	0.011	0.824	0.497–1.366	0.452	2.325	1.322–4.091	0.003	1.023	0.500–2.094	0.950

HR hazard ratio, CI confidence interval, H-FABP heart-type fatty acid binding, MBPmean blood pressure, LVEF left ventricular ejection fraction measured on echocardiography, Hs-TropT high-sensitivity troponin T, Nt-proBNP N-Terminal pro-brain-type natriuretic peptide