Table 4.
Cox regression analysis of the associations between 180-day cumulative mortality and the clinical findings
| Univariate analysis | Multivariate analysis | |||||
|---|---|---|---|---|---|---|
| 180-days mortality | HR | 95 % CI | p value | HR | 95 % CI | p value |
| H-FABP level and AKI status | ||||||
| H-FABP≦15.6 and no-AKI | 1.000 | 1.000 | ||||
| H-FABP≦15.6 and AKI | 4.128 | 1.432–11.898 | 0.009 | 2.676 | 0.920–7.783 | 0.071 |
| H-FABP≧15.7 and no-AKI | 8.070 | 3.592–18.131 | <0.001 | 9.268 | 3.835–22.396 | <0.001 |
| H-FABP≧15.7 and AKI | 14.037 | 6.556–30.054 | <0.001 | 11.593 | 5.154–26.078 | <0.001 |
| Adjusting factors | ||||||
| Chronic kiedney disease | 0.887 | 0.560–1.405 | 0.609 | |||
| Age (≧69 years old) | 1.036 | 0.659–1.629 | 0.879 | |||
| MBP (≧99 mmHg) | 0.205 | 0.114–0.366 | <0.001 | 0.239 | 0.130–0.441 | <0.001 |
| LVEF (≧51 %) | 0.652 | 0.396–1.074 | 0.093 | |||
| Hemoglobin (≧13.5 g/dl) | 0.567 | 0.352–0.912 | 0.019 | 0.990 | 0.603–1.624 | 0.968 |
| Hs-TropT (≧0.064 ng/ml) | 2.429 | 1.478–3.994 | <0.001 | 0.818 | 0.469 –1.424 | 0.477 |
| Nt-ProBNP (≧930 pg/ml) | 1.598 | 1.001–2.552 | 0.050 | |||
HR hazard ratio, CI confidence interval, H-FABP heart-type fatty acid binding, MBP mean blood pressure, LVEF left ventricular ejection fraction measured on echocardiography, Hs-TropT high-sensitivity troponin T, Nt-proBNP N-Terminal pro-brain-type natriuretic peptide