Table 2.

Joinpoint regression analysis of epidemiological indicators related to leprosy, 2001–2012

Indicator	State	Annual percentage change (APC)			Average annual percentage change (AAPC)
		Period	APC	95 % CI	Intire period	AAPC	95 % CI
Incidence rates of leprosy per 100,000 inhabitants	Aggregated of municipalities	2001–2003	5.8	−5.3 a 18.1	2001–2012	−4.2*	−5.9 a −2.4
		2003–2012	−6.2*	−7.2 a −5.2
	Rondônia	2001–2004	4.7	−4.7 a 14.9	2001–2012	−4.1*	−6.5 a −1.7
		2004–2012	−7.2*	−9.3 a −5.1
	Pará	2001–2003	5.2	−13.1 a 27.3	2001–2012	−5.3*	−8.3 a −2.3
		2003–2012	−7.5*	−9.3 a −5.8
	Tocantins	2001–2008	0.6	−1.9 a 3.1	2001–2012	−3.3*	−5.5 a −1.1
		2008–2012	−9.7*	−15.2 a −4.0
	Maranhão	2001–2004	4.5	−5.0 a 15.0	2001–2012	−3.4*	−5.8 a −1.0
		2004–2012	−6.3*	−8.3 a −4.2
	Mato Grosso	2001–2012	−5.2*	−6.2 a −4.3	2001–2012	−5.2*	−6.2 a −4.3
	Other states of Brazil	2001–2003	6.3	−1.4 a 14.6	2001–2012	−4.0*	−5.2 a −2.8
		2003–2012	−6.2*	−6.9 a −5.5
Incidence rates of leprosy in children <15 years per 100,000 inhabitants	Aggregated of municipalities	2001–2003	6.0	−10.1 a 24.9	2001–2012	−3.6*	−6.2 a −1.0
		2003–2012	−5.6*	−7.2 a −4.1
	Rondônia	2001–2012	−3.0	−7.5 a 1.7	2001–2012	−3.0	−7.5 a 1.7
	Pará	2001–2012	−5.3*	−6.9 a −3.7	2001–2012	−5.3*	−6.9 a −3.7
	Tocantins	2001–2012	−0.9	−4.0 a 2.3	2001–2012	−0.9	−4.0 a 2.3
	Maranhão	2001–2012	−3.5*	−5.6 a −1.4	2001–2012	−3.5*	−5.6 a −1.4
	Mato Grosso	2001–2012	−5.9*	−7.8 a −3.9	2001–2012	−5.9*	−7.8 a −3.9
	Other states of Brazil	2001–2003	7.9	−1.7 a 18.5	2001–2012	−2.7*	−4.2 a −1.2
		2003–2012	−4.9*	−5.8 a 4.0
Rates of new cases with grade-2 disabilities per 100,000 inhabitants	Aggregated of municipalities	2001–2012	−1.3	−2.6 a 0.1	2001–2012	−1.3	−2.6 a 0.1
	Rondônia	2001–2003	52.1	−33.8 a 249.0	2001–2012	0.9	−11.3 a 14.8
		2003–2012	−7.8*	−13.9 a −1.4
	Pará	2001–2012	−2.2	−4.4 a 0.1	2001–2012	−2.2	−4.4 a 0.1
	Tocantins	2001–2012	−0.4	−3.0 a 2.2	2001–2012	−0.4	−3.0 a 2.2
	Maranhão	2001–2004	−0.4	−2.8 a 2.1	2001–2012	−0.4	−2.8 a 2.1
	Mato Grosso	2001–2012	−0.3	−2.7 a 1.9	2001–2012	−0.3	−2.7 a 1.9
	Other states of Brazil	2001–2008	0.2	−2.0 a 2.5	2001–2012	−2.6*	−4.3 a −0.9
		2008–2012	−7.4*	−11.3 a −3.2

*Significantly different from 0 (p <0.05)

95 % CI: 95 % confidence intervals