Table 2.
Time since presentation to emergency department | Total medication doses over 24-hour period | Daily chlorpromazine equivalence | Daily diazepam equivalence |
---|---|---|---|
0–24 hours | Lorazepam IV/IM 10 mg | 50 mg | |
Ziprasidone IM 60 mg | 300 mg | ||
Droperidol IM 45 mg | 900 mg | ||
Zuclopenthixol acetate IM 150 mg | 300 mg | ||
Benztropine IM 2 mg | |||
24–48 hours | Lorazepam IM 6 mg | 30 mg | |
Droperidol IM 100 mg | 2000 mg | ||
Zuclopenthixol acetate IM 150 mg | 300 mg | ||
48–72 hours | Lorazepam IM 8 mg | 40 mg | |
Lorazepam PO 2 mg | 10 mg | ||
Droperidol IM 50 mg | 1000 mg | ||
Zuclopenthixol acetate IM 100 mg | 200 mg | ||
Chlorpromazine PO 300 mg | 300 mg | ||
72–96 hours | Lorazepam PO 16 mg | 80 mg | |
Chlorpromazine PO 1350 mg | 1350 mg | ||
Zuclopenthixol acetate IM 100 mg | 200 mg | ||
Benztropine PO 2 mg | |||
96–120 hours | Lorazepam PO 10 mg | 50 mg | |
Chlorpromazine PO 750 mg | 750 mg | ||
Zuclopenthixol decanoate IM 300 mg | 450 mga | ||
Benztropine PO 2 mg |
Daily chlorpromazine and diazepam equivalence are provided for comparative purposes [31]. IM intramuscular, IV intravenous, PO oral. aZuclopenthixol decanoate depot of 300 mg/fortnightly is equivalent to 450 mg of chlorpromazine daily over the fortnight