Table 1:

Evaluation of biomarkers of post-traumatic sepsis

Biomarkers of post-traumatic sepsis	Predictive value	Study
PCT	Yes	[27,28,30–34]
CRP	No	[4,28,30–32,40–43]
IL-6	Controversial	Yes [31,32]
		No [42,43,47–50]
IL-10	Yes	[4, 53–56]
Neopterin	No	[42, 58–60]
PSP/reg	Yes	[32]
IL-1	Yes	[55]
NT-proCNP	Yes	[66]
PMNE	Controversial	Yes [47, 59]
		No [42, 43]
Lactate clearance	Yes	[31, 68]
IL-18	Yes	[58]
mHLA-DR	Yes	[72, 73]
TNF-α	No	[60]
TLR-9	Yes	[74]
PMN CD11b	Yes	[49]
sFAS	Yes	[47]
Gc-globulin	Yes	[75]
s-TM	Yes	[77]
kynurenine values and kynureninetryptophan ratio	Yes	[76]

PCT = Procalcitonin, CRP = C-reactive protein, IL = Interleukin, PSP/reg = Pancreatic stone protein/regenerating protein, NT-proCNP = Amino-terminal pro-peptide, PMNE = Polymorphonuclear elastase, mHLA-DR = Monocyte Human Leukocyte Antigen DR, TNF-α = Tumor necrosis factor α, TLR-9 = Toll-like receptor-9, PMN CD11b = Polymorphonuclear cluster of differentiation 11b, sFAS = Soluble FAS, Gc-globulin = Group-specific component globulin, s-TM = Soluble thrombomodulin