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. 2016 Sep 6;35(1):135. doi: 10.1186/s13046-016-0410-3

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© The Author(s). 2016

Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Fig. 3 — In silico analysis using Alamut software. ATM variants identified in PBMCs derived from two familial breast cancer patients (BC patient#1 and #2) and one breast-thyorid cancer patient (BTC patient#7) lead to an increased affinity and/or appearance of a de novo sites for SR proteins