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. 2016 Jul 14;33(8):557–574. doi: 10.1007/s40266-016-0381-2

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© The Author(s) 2016

Open AccessThis article is distributed under the terms of the Creative Commons Attribution-NonCommercial 4.0 International License (http://creativecommons.org/licenses/by-nc/4.0/), which permits any noncommercial use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made.

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Fig. 2 — Quality of life in opioid-treated patients classified as having advanced illness (severe, non-curable disease and relatively short life-expectancy) or non-advanced illness (disabling but not life-threatening chronic condition) based on a PAC-QOL sum scores (higher scores indicate lower quality of life) and b the EQ-5D index (lower scores indicate lower quality of life). EQ-5D EuroQOL-5 Dimensions, PAC–QOL Patient Assessment of Constipation–Quality of Life.

(Adapted from [74], reprinted by permission of Informa Healthcare)