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. 2016 Aug 22;408(24):6857–6868. doi: 10.1007/s00216-016-9812-5

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© The Author(s) 2016

Open Access This article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made.

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Fig. 2 — Comparison of the mass spectra in the gray and white matter regions obtained from a brain tissue section within the intact lipid mass range (m/z 700–900) using a 40 keV Ar₄₀₀₀ ⁺ GCIB SIMS on the nanoparticle-modified tissue, b MALDI with DHB sublimation, and c gold NP-LDI. The spectra for all methods were normalized to total ion counts in the whole spectrum (In SIMS ×10⁹ for gray matter and ×10⁴ for white matter)