Figure 6.
African Americans ≥35 years old. Interlobular artery intimal thickening (transformed) versus MAP by APOL1 risk allele status. Shown are relationships by linear regression between the percent interlobular artery intimal thickening (Itr) transformed as log10 (Itr + 10) and MAP by APOL1 genotype. In multivariable regression, there is a significant difference between the alleles (0 vs. 1, P = 0.99, normality = 0.72, constant variance = 0.23, α = 0.05:0.986; 0 vs. 2, P = 0.019, normality = 0.24, constant variance = 0.58, α = 0.05:0.996; 1 vs. 2, P = 0.016, normality = 0.65, constant variance = 0.08, α = 0.05:0.982).