Table 8.

African Americans ≥35 years old

Risk genotype	Itr	Itr/MAP
0	11.0 ± 8.2	0.09 ± 0.07
1	11.0 ± 7.8	0.09 ± 0.06
2	15.9 ± 13.3	0.15 ± 0.10
P, 0 vs. 1	0.88	0.80
P, 0 vs. 2	0.15	0.02
P, 1 vs. 2	0.19	0.03

Comparisons by Wilcoxon rank sum tests between APOL1 risk allotypes for Itr and Itr divided by MAP. The Itr (% intimal thickening of interlobular arteries) phenotype as a response to mean arterial blood pressure (MAP) is recessive, that is, risk genotype 2 > risk genotype 0 or 1.